Compiled by Sperry Krueger
North Carolina Biotechnology Center Library
August 18, 2003
Bouchie, Aaron. “Private biotech companies face new funding challenges.” Bioe News. (Bioentrepreneur website from Nature Publishing Group) Published online July 24, 2003.
Chea, Terence. “Biotech firms thwarted by bureaucracy; Industry seeks a liaison office to help navigate government’s biodefense efforts.” The Washington Post. February 7, 2002.
Chiruvolu, Ravi. “Before you do that amazing biotech deal, read this story.” Venture Capital Journal. August 1, 2002.
http://www.charterventures.com/news/vcj_biotechdeal_rep.pdf
Dibner, Mark D. and Michael Howell. “Finding Funding in Biotechnology: Keeping the Companies Alive.” BioPharm. June 2002.
Directory of Biomedical and Health Care Grants, 2003. 17th edition. Oryx Press.
(The 2004 / 18th edition is expected to be published in October2003.)
http://www.greenwood.com/books/BookDetail.asp?sku=OXHCG03&imprintID=I0
Dooley, Joseph F. III and Joseph F. Dooley, Jr. “Convincing a venture capitalist to invest in your idea.” Bioentrepreneur, supplement to Nature Biotechnology. July 2003.
http://www.dooley.com/nature.pdf
Duca, John V., and Mine K. Yücel. “An Overview of Science and Cents: Exploring the Economics of Biotechnology.” Federal Reserve Bank of Dallas Economic and Financial Policy Review, Vol. 1, No. 3, 2002.
http://dallasfedreview.org/pdfs/v01_n03_a01.pdf.
Firstenberg, Paul B. Philanthropy’s Challenge: Building Nonprofit Capacity Through Venture Grantmaking. The Foundation Center. 2003.
Ordering information: http://fdncenter.org/learn/bookshelf/pc/summary.html.
Fleischer-Black, Matt. “Patient, heal thyself.” Corporate Counsel. June 11, 2002.
The Foundation Center's Guide to Grantseeking on the Web. The Foundation Center. 2003 edition will be available in September 2003.
Ordering information: http://fdncenter.org/learn/bookshelf/grantseek/summary.html.
Gaither, Chris. “NIH rule hits some biotech start-ups; Firms controlled by venture capitalists ineligible for grants.” The Boston Globe. July 5, 2003.
Lawlor, Michael S. “Biotechnology and Government Funding: Economic Motivation and Policy Models.” Prepared for Science and Cents: The Economics of Biotechnology, Federal Reserve Bank of Dallas, April 19, 2002. http://www.dallasfed.org/htm/dallas/events/archive/lawlor.pdf
Mitchell, Phyllis. “National Institutes of Health: Small Business Funding OpportuNIHtie$”
Presentation on Government Funding Sources from BioEntrepreneur Symposium, May 11, 2002. http://www.eagleman.com/bioentrepreneur2002/Presentations/NIH_files/frame.htm
Park, Paula. “Taking a Discovery to Market.” The Scientist.
Part 1, “Selling the Story of a Discovery,” published on November 12, 2001 – http://www.the-scientist.com/yr2001/nov/prof1_011112.html
Part 2, “Climbing the Money Tree,” published on November 26, 2001 – http://www.the-scientist.com/yr2001/nov/prof2_011126.html
Part 3, “Dealing in Relationships,” published on December 10, 2001 – http://www.the-scientist.com/yr2001/nov/prof2_011126.html
Purcell, Dennis J. "Financing Biotechnology in an Inefficient Market." Bioentrepreneur, supplement to Nature Biotechnology. May 1999.
Stone, Jim. “Finding the funding.” AFP Exchange. May 1, 2002.
“Venture Philanthropy: New Money for New Cures” was the title of a session at the Massachusetts Biotechnology Council’s annual meeting on April 24, 2003. The description of the program was as follows: “With traditional financing markets remaining weak, new development models have emerged from unlikely places to support innovation in the treatment of serious diseases. Foundations are moving from ‘grantor’ roles and venturing into ‘investor’ roles. Will this be a sustainable new source of capital formation for the biotech industry?”
Two presentations from the session are available online:
· Kim Hunter-Schaedle, PhD, Associate Director, Industry Relations, Juvenile Diabetes Research Foundation International http://www.massbio.org/programs/annual_mtg/2003/Presentations/Hunter-Schaedle.ppt
· Lorenzo Refolo, PhD, Scientific Director, Institute for the Study of Aging http://www.massbio.org/programs/annual_mtg/2003/Presentations/Refolo.ppt
There are various ways to search for funding opportunities. Here are a few well-known sources…
The Community of Science Funding Opportunities database is a comprehensive source of funding information, with more than 23,000 records that represent over 400,000 funding opportunities worth over $33 billion. The database can be searched by keyword, sponsor, sponsor type, funding type, amount, etc.
More information is available at http://fundingopps.cos.com/.
(Note: The North Carolina Biotechnology Center’s Library has subscription access to COS.)
CRISP (Computer Retrieval of Information on Scientific Projects) is a searchable database of federally funded biomedical research projects conducted at universities, hospitals, and other research institutions. The database, maintained by the Office of Extramural Research at the National Institutes of Health, includes projects funded by the National Institutes of Health (NIH), Substance Abuse and Mental Health Services (SAMHSA), Health Resources and Services Administration (HRSA), Food and Drug Administration (FDA), Centers for Disease Control and Prevention (CDCP), Agency for Health Care Research and Quality (AHRQ), and Office of Assistant Secretary of Health (OASH). Users can use the CRISP interface to search for scientific concepts, emerging trends and techniques, or identify specific projects and/or investigators. CRISP does not include financial information so you cannot use this database to see how much money was awarded.
Other information about grants from the National Institutes of Health can be found at the NIH Grants and Funding Opportunities web page at http://grants1.nih.gov/grants/.
The Foundation Directory is a comprehensive directory providing descriptions of more than 41,000 grantmakers, including private grant-making foundations, community foundations, operating foundations, and corporate grant makers. Records include entries from the following Foundation Center print publications: The Foundation Directory, The Foundation Directory, Part 2, New York State Foundations, Guide to U.S. Foundations, and National Directory of Corporate Giving. The center defines a foundation as a nongovernmental, nonprofit organization with its own funds (usually from a single source, either an individual, family or corporation) and program managed by its own trustees and directors. Principal sources of information are voluntary reports by many grant makers directly to the Foundation Center and information obtained from public information returns filed each year with the Internal Revenue Service by private foundations.
Individuals can subscribe to the Foundation Directory database at http://fconline.fdncenter.org/ or search using Dialog file 26 (http://library.dialog.com/bluesheets/html/bl0026.html).
(Note: The North Carolina Biotechnology Center’s Library has subscription access to Dialog.)
Foundation Grants Index contains records describing grants that have been awarded to nonprofit organizations by the larger independent, corporate, and community foundations (over 1,000 in 1995) located in the United States. This file cumulates grant records published in the Foundation Grants Index Annual and Foundation Grants Index Quarterly issues. Designed primarily to serve grant-seeking nonprofit organizations in determining private grantmakers' funding interests, it also serves grantmakers and researchers as a repository of historic information about private philanthropic activity.
Individual subscribers can search grants using the Foundation Directory databases at http://fconline.fdncenter.org/ or search using Dialog file 27 (http://library.dialog.com/bluesheets/html/bl0027.html).
(Note: The North Carolina Biotechnology Center’s Library has subscription access to Dialog.)
Grants, produced by Oryx Press, an imprint of the Greenwood Publishing Group, Inc., provides information on more than 10,000 available grants offered by federal, state, and local governments, commercial organizations, associations, and private foundations. Each entry includes full description, qualifications, money available, and renewability. Full name, address, and telephone number for each sponsoring organization, if available, are also included. The Grants database corresponds to the print publications Directory of Research Grants, Directory of Biomedical and Health Care Grants, Directory of Grants in the Humanities, Funding Sources for Community and Economic Development, Funding Sources for K-12 Schools and Educational Organizations and Operating Grants for Nonprofit Organizations.
Individuals can subscribe to a web version of this database – called GrantSelect – at http://www.grantselect.com/. The Grants database is file 85 on Dialog (http://library.dialog.com/bluesheets/html/bl0085.html).
(Note: The North Carolina Biotechnology Center’s Library has subscription access to Dialog.)
Universities across North Carolina have put together tutorials, guides and links to help researchers find funding and write proposals. Here are a few…
Duke University, Office of Research Support
http://www.ors.duke.edu/find/index.html
(In particular, see the “Funding Search Tutor” written by Ann Kaplan at http://www.ors.duke.edu/find/tools/tutor.html.)
East Carolina University, Office of Sponsored Research
http://www.research2.ecu.edu/osp/
North Carolina State University, Sponsored Programs and Regulatory Compliance (SPARC)
http://www.ncsu.edu/sparcs/funding.html
University of North Carolina at Chapel Hill, Research at Carolina - Find Funding Sources
http://research.unc.edu/services/find_funding.html
University of North Carolina at Charlotte, Office of Proposal Development
http://www.uncc.edu/research/Fund/funding.asp
University of North Carolina at Greensboro, Office of Research Services
http://www.uncg.edu/rss/funding.htm
Wake Forest University, Research and Sponsored Programs
http://www.wfu.edu/rsp/funding.html
As an example, here are a handful of the foundations that support biotechnology research and/or companies …
ABC2, Accelerate Brain Cancer Cure, is a 501(c)(3) tax-exempt, non-profit association dedicated to accelerating a brain cancer cure. They have “a number of planned collaborations with industry, working with Genentech on two different programs and a unique partnership with Ingenuity and CaP CURE.”
Note that ABC2 has
already has a link to North Carolina. They provide funding to Duke University
to screen “up to 12 new molecules per year. This screening is done at no cost
to the drug companies that provide these molecules for testing. As a result,
the number of molecules being screened has risen dramatically and the economic
barrier to the drug companies for this preclinical screening is eliminated.
Through this important investment, we hope to identify new and promising
therapies for brain cancer patients.”
The ALS Therapy Development Foundation is a nonprofit biotechnology company discovering treatments for patients alive today. Our approach combines the power of a nonprofit mission with the best practices of a for-profit biotechnology company: rigorous, open-minded research and proven drug development techniques.
http://www.als-tdf.org/alstdf/default.asp
The Bill and Melinda Gates Foundation’s global health initiative funds research on vaccines for AIDS as well as many other global health problems.
http://www.gatesfoundation.org/
CaP CURE, a nonprofit public charity, is the largest private source of funding for prostate cancer research in the world. Since its inception in 1993, CaP CURE has awarded more than $104 million to fund 1,000 medical research projects worldwide.
The Institute for the Study of Aging (ISOA) is a biomedical venture philanthropy whose mission is to catalyze and fund the discovery and development of new therapies to prevent and treat Alzheimer's disease. Since 1998, ISOA has committed more than $18 million in support of 80 research projects at leading academic institutions and biotechnology companies in 7 countries. ISOA is a New York-based private foundation endowed by the Estée Lauder Trust.
http://www.aging-institute.org/
The Juvenile Diabetes Research Foundation International (JDRF) is the leading charitable funder and advocate of juvenile (type 1) diabetes research worldwide. The mission of JDRF is to find a cure for diabetes and its complications through the support of research.
The Michael J.
Fox Foundation for Parkinson’s Research “is
dedicated to ensuring the development of a cure for Parkinson's disease within
this decade through an aggressively funded research agenda.”
http://wwwmichaeljfox.org/